ARTICLES

2024
Comparison of reaction networks of insulin signaling.
P.V. Lubenia, E. Mendoza, A. Lao.
Uploaded to arXiv

Research landscape of Filipino mathematicians: A co-authorship network analysis.
P. Yu, G. Aurellano, E. Guanzon, E. Templonuevo, U. Chua, B. Samson, J.R. Delos Santos, A. Lao.
Philippine Journal of Science, 153 (4): 1277-1284, August 2024

Fans and Health Information Network on X.
J.M.A. Bernades, E. Chan, M.R. Chan, S.J. Ching, S.L. Sie, A. Lao, C. Cheng.
Submitted

Health Communication Modeling Framework.
F. Yusoph, J.M.A. Bernades, C. Cheng, A. Lao.
Submitted

P-Graph Approach to Modeling Sustainable Ecological Networks.
M.B. Merlin, A. Lao.
In: Abraham, Martin A. (eds.) Encyclopedia of Sustainable Technologies, 2nd Edition, vol. 1, pp. 394-406. Oxford: Elsevier, 2024

Epidemiological Modeling of Health Information Dynamics on Twitter.
F. Yusoph, J.M.A. Bernades, C. Cheng, A. Lao.
Asia-Pacific Social Science Review, 24 (1), March 2024.

Comparative Analysis of Kinetic Realizations of Insulin Signaling.
P.V. Lubenia, E. Mendoza, A. Lao.
Journal of Theoretical Biology, 577, 111672, 2024.

2023
Network modeling for post-entry management of invasive pest species in the Philippines: The case of the Colorado potato beetle, Leptinotarsa decemlineata (Say, 1824) (Coleoptera: Chrysomelidae).
B.J. Almarinez, D. Amalin, K. Aviso, H. Cabezas, A. Lao, R. Tan.
Insects 2023, 14(9), 731; https://doi.org/10.3390/insects14090731.

Modelling Network Effects of Biological Control: The Case of the Philippine Coconut Scale Insect Outbreak.
B.J. Almarinez, D. Amalin, K. Aviso, H. Cabezas, A. Lao, R. Tan.
BioControl, 68, pages117–130 (2023). https://doi.org/10.1007/s10526-023-10188-4

Activation of T-cells and activity of macrophages among smokers with leptospirosis: a synergistic dynamics in the impairment of human immune system.
D.E. Sumalapao, A. Lao, A. Adriano, J.C. So, N. Gloriani.
Brazilian Archives of Biology and Technology, 66, e23220183, 2023.

2022
Mathematical Modeling of Fluconazole Resistance in the Ergosterol Pathway of Candida albicans.
P. Yu, L. Moron-Espiritu, A. Lao.
Msystems, e00691-22.

Reaction Network Analysis of Metabolic Insulin Signaling.
P. Lubenia, E. Mendoza, A. Lao.
Bulletin of Mathematical Biologythis link is disabled, 2022, 84(11), 129.

How Health Information Spreads in Twitter: The Whos and Whats of Philippine TB-data.
E. Chan, M. Chan, S. Ching, S. Sie, A. Lao, J. Bernadas and C. Cheng.
In Proceedings of the 15th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2022) - HEALTHINF; ISBN 978-989-758-552-4; ISSN 2184-4305, SciTePress, pages 421-429. DOI: 10.5220/0010818000003123.

Maintaining the Resilience and Productivity of Co-culture Systems in the Face of Environmental Change.
A. Lao, K. Aviso, H. Cabezas, R. Tan.
Nature Sustainability 5 (9), 749-752.

Concentration Robustness in LP Kinetic Systems.
A. Lao, P. Lubenia, D. Magpantay, E. Mendoza.
MATCH Communication in Mathematical and Computer Chemistry, 88, 29-66.

Modelling the Effects of Medium-Chain Triglycerides on Cerebral Ketone Body Metabolism.
A. Espina, E. Mendoza, A. Lao
Frontiers in Systems Biology, 2, 907957.

Stochastic Process Algebra Model of Amyloidogenic Processing in Alzheimer’s Disease.
A. Lao, M.A. Dela Cruz, G.J. Tenio, P. Sy, E. Mendoza.
In Towards Intelligent Systems Modeling and Simulation, 249-263. Springer, Cham.

2021
Modelling vicious networks with P-graph causality maps.
R. Tan, K. Aviso, A. Lao, M. Promentilla.
Clean technologies and environmental policy 24 (1), 173-184.

P-graph causality maps.
R. Tan, K. Aviso, A. Lao, M. Promentilla.
Process Integration and Optimization for Sustainability 5 (3), 319-334.

2020
Cytotoxic Activity of Raphanus sativus Linn. on Selected Cancer Cell Lines and Mechanistic Pathways Predicted through Mathematical Modeling.
A. Lao, J.M.C. Edra, K.D. Talag, D.S. Tan, G. Oyong, M. Noel, M.L. Enriquez, M.C. Tan.
In International Workshop on Complex Systems Modelling & Simulation, pp. 175-196. Springer, Singapore, 2019.

CRNet Translator: Building GMA, S-System Models and Chemical Reaction Networks of Disease and Metabolic Pathways.
K. Fields, N. Fortun, G.A. Solano, A. Lao.
In 2020 11th International Conference on Information, Intelligence, Systems and Applications (IISA), IEEE.

PlaPhy-SMD: A Database System of Plants and their Phytochemicals Integrated with Small-Molecule Drugs and their Condition and Gene Associations with Clustering and Product Ingredient Matching.
JM Recario, G.A. Solano, A. Lao.
In 2020 11th International Conference on Information, Intelligence, Systems and Applications (IISA), IEEE.

P-graph Causality Maps.
R.G. Tan, K. Aviso, A. Lao, M. Promentilla.
Process Integration and Optimization for Sustainability.

A Deterministic Compartmental Modeling Framework for Disease Transmission.
K.J. Villasin, E. Rodriguez, and A. Lao.
In Computational Methods in Synthetic Biology, Second Edition.

Prevention of H5N6 outbreaks in the Philippines using optimal control.
A. Lucido, R. Smith?, A. Lao.
Philippine Science Letters.

Analysis of the co-authorship network of Filipino researchers in deep learning.
A. Lao, U. Chua, B.P. Samson.
Philippine Science Letters.

Extraction and graph representation of disease-disease associations from biomedical journals using support vector machines.
A. Laron, D.S. Tan, N.R. Lim-Cheng, M. Baclig, L. Cornista, M.L. Daroy, A. Lao, and R. Batista-Navarro.
Manuscript submitted for publication.

Structural Properties of an S-system Model of Mycobacterium tuberculosis Gene Regulation.
H. Farinas, E. Mendoza, A. Lao.
Philippine Journal of Science, 149(3), 539-563.

Socio-ecological network structures from process graphs.
A. Lao, H. Cabezas, A. Orosz, F. Friedler, R. Tan.
PLoS ONE.

Constrained Supply Chain Scheduling Model Using Sequential Quadratic Programming Algorithm.
D.E. Sumalapao, L.E. Bagwan, A. Lao.
Journal of Sciences, Islamic Republic of Iran.

A Pancreatic Cancer Detection Support Tool Using Mass Spectrometry Data and Support Vector Machines.
E. Briones, A. Lao, G.A. Solano.
2020 International Conference on Artificial Intelligence and Signal Processing.

2019
Drowning Out Rumor: Dynamical Models of the Interaction between Spreaders of and Exposed to Truth and Rumor Spreading.
M. Feria, M. Oliva, B.P. Samson, and A. Lao.
Philippine Journal of Science 148 (4), 659-686.

Linear conjugacy of chemical kinetic systems.
A. Nazareno, R.P. Eclarin, E. Mendoza and A. Lao.
Mathematical Biosciences and Engineering, 16(6), 8322-8355.

Chemical Reaction Networks: Filipino contributions to their theory and its Applications.
C.P. Arceo, E. Jose, A. Lao, and E. Mendoza.
Philippine Journal of Science, 148(2), 249-261.

A Deficiency Zero Theorem for a class of power-law kinetic systems with non-reactant-determined interactions.
N. Fortun, E. Mendoza, L. Razon and A. Lao.
MATCH Communication in Mathematical and Computer Chemistry, 81, 621-638.

Pathway based Human Disease Clustering and Similarity Analysis Tool Using Frequent Structure Mining.
D. Mendoza, A. Lao and G.A. Solano.
In 2018 9th International Conference on Information, Intelligence, Systems and Applications (IISA), IEEE.

Biological Network Analysis and Subnetwork Extraction Tool.
D. Rodriguez, A. Lao and G.A. Solano.
In 2018 9th International Conference on Information, Intelligence, Systems and Applications (IISA), IEEE.

2018
Robustness in power-law kinetic systems with reactant-determined interactions.
N. Fortun, A. Lao, L. Razon and E. Mendoza.
In Japanese Conference on Discrete and Computational Geometry, Graphs, and Games, pp. 106-121. Springer, Cham, 2018.

A Deficiency-One Algorithm for power-law kinetic systems with reactant-determined interactions.
N. Fortun, E. Mendoza, L. Razon and A. Lao.
Journal of Mathematical Chemistry, 56,2929-2962.

Multistationarity in Earth’s Preindustrial Carbon Cycle Models.
N. Fortun, E. Mendoza, L. Razon and A. Lao.
Manila Journal of Science, 11, 81-96.

Transmission dynamics and control strategies assessment of avian influenza A (H5N6) in the Philippines.
H. Lee and A. Lao.
Infectious Disease Modelling, 3, 35-59.

Reactant subspaces and kinetics of chemical reaction networks.
C.P. Arceo, E. Jose, A. Lao, and E. Mendoza.
Journal of Mathematical Chemistry, 56(2), 395-422.

AuToDiDAC: Automated Tool for Disease Detection and Assessment for Cacao Black Pod Rot.
D.S. Tan, R.N. Leong, A.F. Laguna, C.A. Ngo, A. Lao, D. Amalin, and D. Alvindia.
Crop Protection, 103, 98-102.

Pathway-based human disease clustering tool using self-organizing maps.
J. A. R. Sarmiento, A. Lao and G.A. Solano.
2017 8th International Conference on Information, Intelligence, Systems & Applications (IISA), (pp. 1-6). IEEE.

2017
Reaction networks and kinetics of biochemical systems.
C.P. Arceo, E. Jose, A. Lao, and E. Mendoza.
Mathematical Biosciences, 283, 13-29.

A dynamical analysis of Tuberculosis in the Philippines.
K.J. Villasin, A. Lao, and E. Rodriguez.
Philippine Science Letters, 10 (1), 29-37.

2016
Stability Analysis of the ODE Model Representation of Amyloidogenic Processing in Alzheimer’s Disease in the Presence of SORLA.
H. Alcantara, A. Lao, and L.Ruivivar.
Molecular BioSystems

A Framework for Measuring Infestation Level on Cacao Pods.
DS Tan, RN Leong, AF Laguna, CA Ngo, A. Lao, D Amalin, and D Alvindia.
In 2016 IEEE Region 10 Symposium (TENSYMP), 384-389.

2012
Multicompartmental modeling of SORLA’s influence on amyloidogenic processing in Alzheimer’s disease.
A. Lao, V. Schmidt, Y. Schmitz, T.E. Willnow, and O. Wolkenhauer.
BMC Systems Biology, 6(1):74.

Quantitative modeling of amyloidogenic processing and its influence by SORLA in Alzheimer’s disease.
V. Schmidt, A. Lao, K. Baum, K. Rateitschak, Y. Schmitz, C. Munck Petersen, A. Nykjaer, J. Wolf, O. Wolkenhauer, and T.E. Willnow.
The EMBO Journal, 31(1):187 - 200.

2009
Systems approaches in molecular and cell biology: making sense out of data and providing meaning to models.
O. Wolkenhauer, A. Lao, S. Omholt, and H. Martens.
Proceedings of SPIE, 7343(1): 734318-734318-11.

  CONFERENCE PROCEEDINGS

2024
Applying Two-Layer Stacked Long Short Term Memory Neural Network on AUDUSD Currency.
A Pagaygay, LG Lim and A Lao.
De La Salle University Research Congress.

Aspect-Based Sentiment Classification on Filipino Tweets.
JP Guzman, C Cheng and A Lao.
De La Salle University Research Congress.

Meta-Analysis on the Removal of Microplastics of Biological and Chemical Wastewater Treatment.
RR Dela Rosa, KA Rasing, PM Sy, JR Valdez, P Yu and A Lao.
De La Salle University Senior High School Research Congress.

2020
State Analysis of Three-node Network Motifs using Boolean Model.
P Chan, R Manero, M Te and A Lao.
De La Salle University Research Congress.

2017
Corpus Annotation of Biomedical Journals for a Machine Learning Approach to Automatic Relation Extraction.
A Laron, DS Tan, NR Lim-Cheng, A Lao, and R Batista-Navarro.
Proceedings of the 17th Philippine Computing Science Congress, University of San Carlos, Cebu, Philippines.

2016
Systems Biology Approach of Understanding the Effect of Raphanus sativus Extract on the Pathogenesis of Chronic Myeloid Leukemia, Breast and Colon Cancer.
JMC Edra, KD Talag, ML Enriquez, and A Lao.
De La Salle University Research Congress.

Method for Measuring Infestation Level on Cacao Pods.
DS Tan, RN Leong, AF Laguna, CA Ngo, A Lao, D Amalin, and D Alvindia.
De La Salle University Research Congress.

  SUBMITTED ABSTRACTS/POSTERS/PAPERS IN CONFERENCES

2023
Health Organizations, Celebrity Fans, and Social Media: Mapping Tuberculosis-related Tweets in the Philippines
73rd Annual ICA Conference, Reclaiming Authenticity in Communication
H J.C. Bernadas; E.Y. Chan; M.C. Chan; S.S. Ching; S. Sie; A. Lao; C. Cheng. Toronto, Canada

2019
Systems Biology of Alzheimer’s Disease: Understanding How to Prevent or Delay its Onset or Progression
International Congress for Industrial and Applied Mathematics
Valencia, Spain

Species Subsets and Embedded Networks of S-systems
SIAM conference on Applied Algebraic Geometry
University of Bern, Switzerland

2018
Multi-stationarity Analysis of the Earth’s Pre-industrial Carbon Cycle Models using Chemical Reaction Network Theory
International Congress of Mathematics
Rio de Janeiro, Brazil

2017
A Mathematical Model Explaining the Effect of Raphanus Sativus on Cancer Diseases
Annual Meeting of the Society of Mathematical Biology
University of Utah, USA

Reactant Subspaces of Power Las Kinetic Systems
Mathematical Society of the Philippines Annual Convention
Legaspi Bicol, Philippines

2016
An In-host Dynamics on the Effects of Tabacco Smoking in the Activation of Tcells and Response Activity of Macrophages in Leptospira Infection
International Conference on Mathematical and Computational Modeling of Biological Systems
University of the Philippines, Diliman, Philippines

The Relationship between Type-2 Diabetes and Alzheimer’s Disease Regulated by Insulin Resistance and Insulin-like Growth Factor 1
International Conference on Mathematical and Computational Modeling of Biological Systems
University of the Philippines, Diliman, Philippines

CRNT Polyglot: One Stop Platform for Generating Chemicat Reaction Network Models
International Conference on Mathematical and Computational Modeling of Biological Systems
University of the Philippines, Diliman, Philippines

Chemical reaction network approaches to biochemical systems theory
The Asian Mathematical Conference
Kabupaten Badung, Bali, Indonesia

Modeling the Effect of Raphanus sativus Extract on the Pathogenesis of Chronic Myeloid Leukemia, Breast and Colon Cancer
Hands-on Research on Complex System
The Abdus Salam International Centre for Theoretical Physics, Trieste, Italy

Systems Biology Approach of Understanding the Effect of Raphanus sativus Extract on the Pathogenesis of Chronic Myeloid Leukemia, Breast and Colon Cancer
International Synthetic and Systems Biology Summer School
TaoSciences Research Center, SIAF, Volterra, Italy

Understanding the Effect of Raphanus sativus Extract on the Pathogenesis of Chronic Myeloid Leukemia, Breast and Colon Cancer through Mathematical Modeling
Mathematical Society of the Philippines Annual Convention
Bayfront Hotel, Cebu, Philippines

2015
Stability Analysis of the ODE Model Representation of Amyloidogenic Processing in Alzheimer’s Disease in the Presence of SORLA
3rd Asian Regional Conference on Systems Biology 2015
Hotel Bangi-Putrajaya, Selangor, Malaysia

Pathogenesis with Resistance Genes using Stochastic BioAmbient Calculus
Mathematical Society of the Philippines Annual Convention
Laoag, Philippines

2014
Mathematical Modelling of Insulin Resistance Linking Type 2 Diabetes and Alzheimer’s Disease
International Congress of Mathematics
Seoul, Korea

Stochastic process algebra modeling of APP processing influenced by SORLA in Alzheimer’s Disease
Mathematical Society of the Philippines Annual Convention
Iloilo, Philippines

2012
Regulated trafficking of APP by SORLA in Alzheimer’s disease
Systems Medicine International Conference
Dublin, Ireland

Multi-compartmental modeling of APP processing influenced by SORLA in Alzheimer’s disease
13th International Conference on Systems Biology (ICSB)
Toronto, Canada

2011
Mathematical modeling of APP processing influenced by SORLA in Alzheimer’s disease: when one pathway is not enough
12th International Conference on Systems Biology (ICSB)
Heidelberg/Mannheim, Germany

2010
Quantitative modeling of APP processing influenced by SORLA in Alzheimer’s disease
International Conference on Alzheimer’s Disease 2010
Honolulu, Hawaii

Mathematical modeling of APP processing influenced by SORLA in Alzheimer’s disease: two pilot models
Mid-term review of the Helmholtz Alliance on Systems Biology
DKFZ, Heidelberg, Germany